80282-58-2Relevant academic research and scientific papers
Iron-Catalyzed Synthesis of Substituted Thiazoles from Enamines and Elemental Sulfur through C?S Bond Formation
Wu, Mingzhong,Jiang, Yong,An, Zhenyu,Qi, Zhenjie,Yan, Rulong
, p. 4236 - 4240 (2018/09/20)
An atom economical approach for the synthesis of substituted thiazoles starting from enamines and elemental sulfur through the C?H functionalization/C?S bond formation is described. Under the optimized conditions, various substituted enamines reacted smoothly with elemental sulfur and the desired substituted thiazoles were generated in moderate to excellent yields. (Figure presented.).
The Reaction of 3,5-Diphenyl-1,2,4-dithiazol-1-ium Perchlorate with Active Methylene Compounds
Shibuya, Isao
, p. 605 - 606 (2007/10/02)
The reaction of 3,5-diphenyl-1,2,4-dithiazol-1-ium perchlorate with several kinds of active methylenes gives a number of heterocycles, such as 4-hydroxy and 4-mercaptopyrimidine, pyrimidinone, and thiazole derivatives.On treatment with hydroxylamine-O-sulfonic acid, the 4-mercaptopyrimidines lead to the aminothio compounds or the isothiazolopyrimidine.
TRISUBSTITUTED THIAZOLES BY A 6?-ELECTROCYCLIZATION OF IMINOTHIOCARBONYL YLIDES
Corsaro, A.,Tarantello, M.,Purrello, G.
, p. 3305 - 3308 (2007/10/02)
Iminothiocarbonyl ylides are generated by a sulfur ligand exchange reaction of sulfonium salts and undergo a 6?-electrocyclic closure and aromatization to tri substituted thiazoles.Related carbonyl ylides preferred a 4?-electrocyclization.
