C1Q, HUMAN, also known as Complement component C1q, is a crucial protein involved in the innate immune system. It is a key regulator of platelet activation and plays a significant role in inflammatory conditions such as coronary heart disease. C1Q, HUMAN has the ability to inhibit collagen-induced aggregation and enhance the production of reactive oxygen species (ROS), making it a vital component in the body's defense mechanisms.
80295-33-6
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Basic information
- Product Name: C1Q, HUMAN
- Synonyms: C1Q, HUMAN;COMPLEMENT COMPONENT C1Q;COMPLEMENT C1Q, HUMAN;COMPLEMENT C1Q PROTEIN;COMPLEMENT C1Q PROTEIN HUMAN;COMPLEMENT 1Q, HUMAN;COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM;activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
- CAS NO:80295-33-6
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /solution ( 10 mM HEPES, pH 7.2. and 0.3 M NaCl )
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: C1Q, HUMAN(CAS DataBase Reference)
- NIST Chemistry Reference: C1Q, HUMAN(80295-33-6)
- EPA Substance Registry System: C1Q, HUMAN(80295-33-6)
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Safety Data
- Hazard Codes: B
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 80295-33-6(Hazardous Substances Data)
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80295-33-6 Usage
Uses
Used in Medical Research:C1Q, HUMAN is used as a research subject for understanding its role in platelet activation and its impact on inflammatory conditions such as coronary heart disease. Its ability to inhibit collagen-induced aggregation and enhance ROS production makes it a valuable tool for studying the underlying mechanisms of these conditions.
Used in Drug Development:
C1Q, HUMAN is used as a target for drug development to modulate its activity and potentially treat inflammatory conditions. By targeting C1Q, HUMAN, researchers can develop therapies that regulate platelet activation and ROS production, potentially leading to new treatments for coronary heart disease and other related conditions.
Used in Diagnostics:
C1Q, HUMAN can be used as a biomarker for diagnosing inflammatory conditions. Its involvement in platelet activation and ROS production makes it a potential indicator of the presence and severity of these conditions. By measuring C1Q, HUMAN levels, healthcare professionals can gain insights into a patient's inflammatory status and make informed decisions regarding treatment options.
Biochem/physiol Actions
≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basisCheck Digit Verification of cas no
The CAS Registry Mumber 80295-33-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,2,9 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.Calculate Digit Verification of CAS Registry Number 80295-33:
(7*8)+(6*0)+(5*2)+(4*9)+(3*5)+(2*3)+(1*3)=126
126 % 10 = 6
So 80295-33-6 is a valid CAS Registry Number.
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C1Q, HUMAN
