80295-65-4

Basic information

• Product Name: FACTOR H, HUMAN
• Synonyms: BETA1H GLOBULIN;BETA1H GLOBULIN, HUMAN;COMPLEMENT FACTOR H;FACTOR H, HUMAN;complement factor H from human plasma
• CAS NO: 80295-65-4
• Molecular Weight: 0
• Product Categories: Complement Factor ProteinsProteins and Derivatives;Complement Proteins;ComplementCell Signaling Enzymes;Plasma Protein CompositionApplication Index;Plasma&Blood Proteins;Plasma, Blood, and Related Proteins and Reagents;Serum Proteins;Serum Proteins and Related Enzymes
• Mol File: 80295-65-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −70°C
• CAS DataBase Reference: FACTOR H, HUMAN(CAS DataBase Reference)
• NIST Chemistry Reference: FACTOR H, HUMAN(80295-65-4)
• EPA Substance Registry System: FACTOR H, HUMAN(80295-65-4)

Safety Data

• Hazard Codes: B
• WGK Germany: 3
• Hazardous Substances Data: 80295-65-4(Hazardous Substances Data)

Usage

Uses

Complement factor H (CFH) is a plasma regulator of the complement protein C3b in the alternative pathway of the complement system. Research has shown that binding of CFH is important for pathogenesis of group A streptococcus (GAS), and inhibition of this binding may be an effective management of GAS infections.

Biochem/physiol Actions

Complement factor H plays an essential role in the homeostasis of the complement system and in preventing collateral damage to bystander cells and tissues by complement activation.