Complement factor I is a regulatory protein found in human plasma that plays a crucial role in the immune system by controlling the activity of the complement system. It is involved in the regulation of the complement cascade, a series of proteolytic reactions that are part of the innate immune response. Complement factor I helps to prevent excessive activation of the complement system, which can lead to tissue damage and inflammation.
80295-66-5
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Basic information
- Product Name: COMPLEMENT FACTOR I
- Synonyms: EC 3.4.21.45;COMPLEMENT FACTOR I;complement factor I from human plasma
- CAS NO:80295-66-5
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: Complement Proteins;ComplementCell Signaling Enzymes;Plasma&Blood Proteins;Plasma, Blood, and Related Proteins and Reagents;Proteolytic Enzymes and Substrates;Proteolytic EnzymesEnzyme Class Index;Complement Factor ProteinsEnzymes, Inhibitors, and Substrates;3.4.x.x Peptidases;3.x.x.x Hydrolases
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −70°C
- Solubility: N/A
- CAS DataBase Reference: COMPLEMENT FACTOR I(CAS DataBase Reference)
- NIST Chemistry Reference: COMPLEMENT FACTOR I(80295-66-5)
- EPA Substance Registry System: COMPLEMENT FACTOR I(80295-66-5)
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Safety Data
- Hazard Codes: B
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 80295-66-5(Hazardous Substances Data)
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80295-66-5 Usage
Uses
Used in Medical Research:Complement factor I is used as a research tool for studying the human complement cascade of proteolysis and its regulation. It is particularly useful in understanding the mechanisms of complement activation and the role of complement factor I in controlling the immune response.
Used in Microbiology:
Complement factor I from human plasma has been used in a case study of glucose-starved Staphylococcus aureus. This research helps to understand the interaction between the complement system and bacterial pathogens, which can provide insights into the development of new treatments for bacterial infections.
Used in Phototherapy Research:
Complement factor I has also been used to study the human complement cascade as a target of laser irradiation. This research can contribute to the development of new phototherapy techniques for the treatment of various diseases, including cancer and inflammatory conditions, by targeting the complement system.
Biochem/physiol Actions
Protease which cleaves and inactivates C3b and C4bCheck Digit Verification of cas no
The CAS Registry Mumber 80295-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,2,9 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.Calculate Digit Verification of CAS Registry Number 80295-66:
(7*8)+(6*0)+(5*2)+(4*9)+(3*5)+(2*6)+(1*6)=135
135 % 10 = 5
So 80295-66-5 is a valid CAS Registry Number.
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COMPLEMENT FACTOR I
