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4-BROMO-1-VINYL-1H-PYRAZOLE is a pyrazole derivative with the molecular formula C6H5BrN2, featuring a bromine atom and a vinyl group attached to the pyrazole ring. This chemical compound is utilized in organic synthesis and has demonstrated potential biological activities and medicinal properties.

80308-80-1

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80308-80-1 Usage

Uses

Used in Pharmaceutical Industry:
4-BROMO-1-VINYL-1H-PYRAZOLE is used as a building block for the preparation of various pharmaceuticals due to its unique structure and reactivity, which allows for the production of complex molecules.
Used in Agrochemical Industry:
4-BROMO-1-VINYL-1H-PYRAZOLE is also used as a building block in the synthesis of agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Anticancer Applications:
4-BROMO-1-VINYL-1H-PYRAZOLE has been studied for its potential as an anticancer agent, showing promise in the development of new treatments for cancer.
Used in Antiviral Applications:
Additionally, 4-BROMO-1-VINYL-1H-PYRAZOLE has been investigated for its potential in antiviral drug development, indicating its versatility in medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 80308-80-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,0 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 80308-80:
(7*8)+(6*0)+(5*3)+(4*0)+(3*8)+(2*8)+(1*0)=111
111 % 10 = 1
So 80308-80-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrN2/c1-2-8-4-5(6)3-7-8/h2-4H,1H2

80308-80-1Downstream Products

80308-80-1Relevant academic research and scientific papers

Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors

Acton, John J.,Adpressa, Donovon,Ardolino, Michael J.,Bennett, David Jonathan,Chau, Ryan W.,Ciaccio, Paul J.,Dimauro, Erin F.,Faltus, Robert,Fell, Matthew J.,Fuller, Peter H.,Gulati, Anmol,Hegde, Laxminarayan G.,Johnson, Rebecca E.,Kattar, Solomon D.,Kennedy, Matthew E.,Keylor, Mitchell H.,Lesburg, Charles A.,Lin, Shishi,Liu, Ping,Margrey, Kaila A.,McMinn, Spencer E.,Morriello, Gregori J.,Neelamkavil, Santhosh,Nogle, Lisa,Otte, Karin M.,Palte, Rachel L.,Piesvaux, Jennifer,Pio, Barbara,Poremba, Kelsey E.,Simov, Vladimir,Su, Jing,Wood, Harold B.,Woodhouse, Janice D.,Xiong, Tina,Yan, Xin,Zarate, Cayetana

, p. 838 - 856 (2022/01/20)

The leucine-rich repeat kinase 2 (LRRK2) protein has been genetically and functionally linked to Parkinson's disease (PD), a disabling and progressive neurodegenerative disorder whose current therapies are limited in scope and efficacy. In this report, we

N-(HETEROARYL) QUINAZOLIN-2-AMINE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

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Page/Page column 68-69, (2021/04/30)

The present invention is directed to substituted certain N-(heteroaryl)quinazolin-2-amine derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein J, R3, and R4, are as defined herein, which are potent inhib

The N-vinyl group as a protection group of the preparation of 3(5)-substituted pyrazoles via bromine-lithium exchange

Iddon, Brian,T?nder, Janne Ejrn?s,Hosseini, Masood,Begtrup, Mikael

, p. 56 - 61 (2007/10/03)

Treatment of 3,4,5-tribromopyrazole with 1,2-dibromoethane and triethylamine gave 3,4,5-tribromo-1-vinylpyrazole, which underwent regioselective bromine-lithium exchange at the 5-position. Subsequent addition of an electrophile gave 5-substituted 3,4-dibr

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