8031-42-3

Basic information

• Product Name: DIGITALIS (3 G)
• Synonyms: FOXGLOVE;DIGITALISLANATA;DIGITALIS (3 G);digitalin(pharmaceutical);digitalis,naturalproducts,pharmaceutical;digitalispurpurea,leaf;digitalone;digitannoid
• CAS NO: 8031-42-3
• Mol File: 8031-42-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DIGITALIS (3 G)(CAS DataBase Reference)
• NIST Chemistry Reference: DIGITALIS (3 G)(8031-42-3)
• EPA Substance Registry System: DIGITALIS (3 G)(8031-42-3)

Safety Data

• Hazardous Substances Data: 8031-42-3(Hazardous Substances Data)

Usage

Biological Functions

Lanatoside A is composed of the aglycone digitoxigenin (genin indicates no sugar) connected to three digitoxose sugar molecules, the third of which carries a 3-acetyl group, and a terminal glucose molecule. In other words, the structure sequence is glucose4-3-acetyldigitoxose3-digitoxose2- digitoxose1-digitoxigenin. Lanatoside B has the identical sugar portion to lanatoside A, except that the aglycone has extra hydroxyl group at C-16 and is given the name gitoxigenin. The structural sequence is glucose4-3- acetyldigitoxose3-digitoxose2-digitoxose1-gitoxigenin. Lanatoside C also has the same sugars found in both lanatosides A and B; however, the aglycone has the nucleus of lanatoside A plus an additional hydroxyl group at C-12. This cardenolide is named digoxigenin. The structural sequence is glucose4-3-acetyldigitoxose3-digitoxose2-digitoxose1- digoxigenin. Partial hydrolysis of the glucose molecule and the acetate group from lanatoside A and C produces, respectively, two new and most important cardiac glycosides, digitoxin and digoxin, with the following sequences: digitoxin, (digitoxose)3-digitoxigenin; and digoxin, (digitoxose)3-digoxigenin.