80312-16-9Relevant academic research and scientific papers
A four component coupling strategy for the synthesis of D-phenylglycinamide-derived non-covalent factor Xa inhibitors
Sheehan, Scott M.,Masters, John J.,Wiley, Michael R.,Young, Stephen C.,Liebeschuetz, John W.,Jones, Stuart D.,Murray, Christopher W.,Franciskovich, Jeffrey B.,Engel, David B.,Weber II, Wayne W.,Marimuthu, Jothirajah,Kyle, Jeffrey A.,Smallwood, Jeffrey K.,Farmen, Mark W.,Smith, Gerald F.
, p. 2255 - 2259 (2007/10/03)
A novel isonitrile derivative was synthesized and used in an Ugi four component coupling reaction to explore aryl group substitution effects on inhibition of the coagulation cascade serine protease factor Xa.
