80314-64-3

Basic information

• Product Name: 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene
• Synonyms: 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene
• CAS NO: 80314-64-3
• Molecular Weight: 214.692
• Mol File: 80314-64-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene(80314-64-3)
• EPA Substance Registry System: 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene(80314-64-3)

Safety Data

• Hazardous Substances Data: 80314-64-3(Hazardous Substances Data)

Usage

General Description

2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene is a chemical compound with the molecular formula C11H15ClO2. It is a derivative of benzene and contains a chlorine atom, a methoxy group, and an ethyl group. The chemical is commonly used in the production of pharmaceuticals and agrochemicals. It has been identified as a potential genotoxic impurity and is subject to strict regulations in the pharmaceutical industry to ensure its safe use. The compound is also used as a building block in organic synthesis, and its properties make it a valuable intermediate for the manufacture of various industrial chemicals.

Upstream product

• 50-00-0 formaldehyd 
• 80314-58-5 1-methoxy-4-(2-methoxyethyl)benzene 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 104-01-8 4-Methoxyphenylacetic acid 

Downstream Products

• 80314-59-6 <2'-methoxy-5'-(2''-methoxyethyl)phenyl>acetonitrile 
• 80314-60-9 2-[2-Methoxy-5-(2-methoxy-ethyl)-phenyl]-3-oxo-butyronitrile 
• 80314-62-1 (E)-2-[2-Methoxy-5-(2-methoxy-ethyl)-phenyl]-3-trimethylsilanyloxy-but-2-enoic acid methyl ester 
• 80314-57-4 1-Methoxy-4-(2-methoxy-ethyl)-2-{1-[1-methoxy-1-trimethylsilanyloxy-meth-(Z)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 
• 80318-67-8 dimethyl 3,6,8-trihydroxy-7-<2'-methoxy-5'-(2''-methoxyethyl)phenyl>-9,10-dioxo-9,10-dihydroanthracene-1,2-dicarboxylate 

Relevant articles and documents

RENIN INHIBITORS

Renin inhibitors, which are spirocyclic piperidine amides, of structural formula (I) and pharmaceutical compositions thereof useful in the treatment of cardiovascular diseases and renal insufficiency, wherein n, for each instance in which it occurs, is independently 0, 1, or 2; R1 is hydrogen, C1-6 -alkyl or C3-6 -cycloalkyl, wherein said C1-6 -alkyl or C3-6 -cycloalkyl group can be independently substituted with 1-3 halogens; A is (i) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic monocyclic ring or (ii) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring which is fused to another five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring, V is a bond or -(C=O)-, -CH(OH)-, -CH2- or =CH-; U is a bond or -CH2-, or for the case when V is =CH-, U is -CH=; X is =CH-, =CF-, =C(OR3)-, or -C=O-; and Y is =CH-, =CF-, =N-, or for the case when X is -C=O-, Y is -N(R3)-.

SYNTHESIS OF THE XANTHOLACCAIC ACID B SYSTEM

The xantholaccaic acid B system has been synthesized for the first time by successive regiospecific Diels-Alder reactions.