80326-86-9

Upstream product

• 80326-85-8 (2S,3S,3aR,5R,6aS,7aR,8S,11S,11aR,11bR,11cR)-5-Methoxy-3,8,11a,11c-tetramethyl-11-(tetrahydro-pyran-2-yloxy)-hexadecahydro-6-oxa-benzo[de]anthracen-2-ol 
• 90295-63-9 (1β,9β,16β)-16-Methoxy-1-<(tetrahydro-2H-pyran-2-yl)-oxy>picras-12-ene 
• 80326-85-8 (1β,9β,12β,16β)-16-Methoxy-1-<(tetrahydro-2H-pyran-2-yl)oxy>picrasan-12-ol 
• 75924-46-8 (1β,9β,16β)-1-hydroxy-16-methoxypicras-12-ene 

Downstream Products

• 80326-84-7 dl-Castelanolide 
• 90295-64-0 (9β,12β,16β)-16-Methoxy-12-(phenylmethoxy)picras-1-en-1-ol Tetramethylphosphorodiamidate 
• 80326-87-0 (9β,12β,16β)-16-Methoxy-12-(phenylmethoxy)picrasan-1-one 

Relevant academic research and scientific papers

Quassinoids: Total Synthesis of dl-Castelanolide

The total synthesis of dl-castelanolide (5) is described, which proceeds in 15,2percent yield from the tetracyclic alcohol 8, thus confirming the structural assignment made via classical methods by Geissman over ten years ago.