80348-66-9 Usage
Description
4-hydroxyisoxazole is a heterocyclic chemical compound with the molecular formula C3H3NO2. It features a five-membered ring structure containing both oxygen and nitrogen atoms, making it a derivative of isoxazole. 4-hydroxyisoxazole is recognized for its potential applications in various fields, including organic synthesis, pharmaceuticals, agrochemicals, and materials science, as well as its pharmacological properties.
Uses
Used in Organic Synthesis:
4-hydroxyisoxazole is utilized as a building block in organic synthesis for the creation of various pharmaceuticals, agrochemicals, and materials due to its unique structural and functional characteristics.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-hydroxyisoxazole is used as a key intermediate for the development of new drugs, leveraging its potential as an anticonvulsant and analgesic agent. Its investigation into neuroprotective and anti-inflammatory properties further highlights its importance in the discovery of novel therapeutic agents.
Used in Agrochemicals:
4-hydroxyisoxazole also finds application in agrochemicals, where it serves as a crucial component in the synthesis of compounds that can protect crops and enhance agricultural productivity.
Used in Materials Science:
In the field of materials science, 4-hydroxyisoxazole is employed for its potential to contribute to the development of new materials with specific properties, such as those with enhanced stability or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 80348-66-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,4 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 80348-66:
(7*8)+(6*0)+(5*3)+(4*4)+(3*8)+(2*6)+(1*6)=129
129 % 10 = 9
So 80348-66-9 is a valid CAS Registry Number.
80348-66-9Relevant articles and documents
Generation of an 4-Isoxazolyl Anion Species: Facile Access to Multifunctionalized Isoxazoles
Morita, Taiki,Fuse, Shinichiro,Nakamura, Hiroyuki
supporting information, p. 13580 - 13584 (2016/10/21)
A direct functionalization of unsubstituted isoxazole (1) was achieved by generation of 4-isoxazolyl anion species (3). An efficient 4-iodination of isoxazole and halogen–metal exchange reaction using a turbo Grignard reagent (iPrMgCl? LiCl) were essentia
Pyrrolidine modulators of chemokine receptor activity
-
, (2008/06/13)
The present invention is directed to pyrrolidine compounds of the formula 1: (wherein R1, R2, R3, R4, R5, R6and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
ISOLATION, STRUCTURE AND SYNTHESIS OF 4-HYDROXYISOXAZOLE (TRIUMFEROL), A SEED GERMINATION INHIBITOR FROM AN AFRICAN PLANT
Kusumi, Takenori,Chang, Conway C.,Wheeler, Margaret,Kubo, Isao,Nakanishi, Koji,Naoki, Hideo
, p. 3451 - 3454 (2007/10/02)
The isolation, characterization and an efficient synthesis of 4-hydroxyisoxazole 1, a plant growth regulator isolated from an African plant is reported.It is a new compound, which despite the simple structure, had eluded synthesis.