80348-78-3

Basic information

• Product Name: 1-phenyl-4,4,4-trichloro-1-butanone
• Synonyms: 1-phenyl-4,4,4-trichloro-1-butanone
• CAS NO: 80348-78-3
• Molecular Weight: 251.54
• Mol File: 80348-78-3.mol

Chemical Properties

• CAS DataBase Reference: 1-phenyl-4,4,4-trichloro-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-4,4,4-trichloro-1-butanone(80348-78-3)
• EPA Substance Registry System: 1-phenyl-4,4,4-trichloro-1-butanone(80348-78-3)

Safety Data

• Hazardous Substances Data: 80348-78-3(Hazardous Substances Data)

Upstream product

• 75-62-7 Bromotrichloromethane 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 104655-94-9 2-bromo-1-phenyl-4,4,4-trichloro-1-butanol 

Relevant articles and documents

ACTIVATION OF POLYHALOALKANES BY PALLADIUM CATALYST. PREPARATION OF γ-TRICHLORO KETONES BY THE PALLADIUM CATALYZED ADDITION REACTION OF BROMOTRICHLOROMETHANE AND CARBON TETRACHLORIDE TO ALLYL ALCOHOLS

The palladium catalyzed reaction of BrCCl3 and CCl4 with allyl alcohols with terminal double bonds afforded γ-trichloro ketones.Pd(OAc)2 combined with tri-o-tolylphosphine in the presence of a base gave the best results.

Palladium-catalysed oxidation of alcohols with carbon tetrachloride, formation of 4,4,4-trichloro ketones from allylic alcohols and carbon tetrachlorid

Pd salts catalyse oxidation of alcohols with CCl4 in the presence of K2CO3. Primary alcohols are oxidised to esters, and secondary alcohols to ketones. CCl4 is converted to CHCl3. The reaction of allylic alcohols bearing a terminal olefinic bond with CCl4 or BrCCl3 in the presence of palladium catalyst at 110° affords 4,4,4-trichloro ketones. At 40°, simple adducts of CCl4 or BrCCl3 having a halohydrin structure are obtained, which are converted to the corresponding trichloro ketones by the catalysis of palladium. Various halohydrins are converted to ketones by Pd catalysis.