80357-06-8Relevant academic research and scientific papers
An Odorless Preparative Method of Sulfides and Thiocarboxylic S-Esters Using 3-(Alkylthio)-1,2-benzisothiazole 1,1-Dioxide
Yamada, Hiroyuki,Kinoshita, Hideki,Inomata, Katsuhiko,Kotake, Hiroshi
, p. 949 - 950 (1983)
It was found that sodium salt of 1,2-benzisothiazole-3(2H)-thione 1,1-dioxide (thiosaccharin) readily reacted with alkyl halide affording 3-(alkylthio)-1,2-benzisothiazole 1,1-dioxide (3).Treatment of 3 with piperidine produces the corresponding alkanethiol in situ quantitatively and subsequent treatment with various electrophiles gives the corresponding sulfides and thiocarboxylic S-esters in good yields.
SYNTHESIS AND REACTION OF 3-(ALKYLTHIO)-1,2-BENZISOTHIAZOLE 1,1-DIOXIDES AS AN ODORLESS CRYSTALLINE EQUIVALENT OF THIOLS
Inomata, Katsuhiko,Yamada, Hiroyuki,Kotake, Hiroshi
, p. 1457 - 1458 (2007/10/02)
It was found that sodium salt of 1,2-benzisothiazol-3(2H)-thione 1,1-dioxide (thiosaccharin) readily reacted with alkyl halide affording 3-(alkylthio)-1,2-benzisothiazole 1,1-dioxide, which very smoothly produced the corresponding alkanethiol by the reaction with piperidine in almost quantitative yield.
