80367-29-9Relevant academic research and scientific papers
Replacement of the butenolide moiety of digitoxigenin by cyclic Michael acceptor systems
Guzman, Angel,Muchowski, Joseph M.,Strosberg, Arthur M.,Sims, John M.
, p. 3241 - 3247 (2007/10/02)
A series of digitoxigenin analogues was prepared in which the butenolide moiety was replaced by other 5- or 6-membered cyclic Michael acceptor systems.Three compounds, 1b, 1c, and 1d showed weak to moderate cardiotonic activity.
