80370-11-2Relevant articles and documents
Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors
Wilt, Stephanie,Kodani, Sean,Valencia, Leah,Hudson, Paula K.,Sanchez, Stephanie,Quintana, Taylor,Morisseau, Christophe,Hammock, Bruce D.,Kandasamy, Ram,Pecic, Stevan
, (2021/11/19)
Fatty acid amide hydrolase (FAAH) is a membrane protein that hydrolyzes endocannabinoids, and its inhibition produces analgesic and anti-inflammatory effects. The soluble epoxide hydrolase (sEH) hydrolyzes epoxyeicosatrienoic acids (EETs) to dihydroxyeico