803706-41-4Relevant academic research and scientific papers
Inhibitors designed for presenilin 1 by means of aspartic acid activation: Preliminary communication
Larbig, Gregor,Zall, Andrea,Schmidt, Boris
, p. 2334 - 2340 (2007/10/03)
γ-Secretase, a multiprotein aspartic protease crucial to Alzheimer's dementia, is not available for NMR experiments and has, so far, escaped crystallization. A positional scan of the aspartic protease by reactive probes may provide the necessary structura
