80376-82-5

Upstream product

• 3963-62-0 2,2-Diphenylethylamine 
• 80376-76-7 N-tert-Butyl-N'-(2,2-diphenyl-ethyl)-N'-methyl-methanediamine 
• 68579-60-2 2-(methylamino)-1-phenylethanol 
• 71-43-2 benzene 
• 80376-68-7 N'-tert-Butyl-N-(2,2-diphenyl-vinyl)-N-methyl-formamidine 
• 86-29-3 Diphenylacetonitrile 
• 122-07-6 N-(methyl)aminoacetaldehyde dimethyl acetal 

Downstream Products

• 7647-54-3 N,N-dimethyl-2,2-diphenyl-ethyl-1-amine 
• 140945-04-6 N,N'-Diallyl-6-{4-[(2,2-diphenyl-ethyl)-methyl-amino]-piperidin-1-yl}-[1,3,5]triazine-2,4-diamine 
• 1204659-20-0 4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-N-(2,2-diphenylethyl)-N-methylbutanamide 
• 374081-53-5 2-benzoyl-N-{[(2,2-diphenyl-ethyl)-methyl-carbamoyl]-phenylmethyl}-N-[2-(1H-imidazol-4-yl)-ethyl]-benzamide 

Relevant academic research and scientific papers

Chemistry of dicationic electrophiles: superacid-catalyzed reactions of amino acetals.

Amino acetals are shown to form highly electrophilic systems in Bronsted superacids. It is proposed that amino acetals give dicationic electrophiles, and this proposal is supported by the direct observation of a dication by low-temperature (13)C NMR. When reacted with C(6)H(6) and superacidic CF(3)SO(3)H, amino acetals are shown to provide 1-(3,3-diphenylpropyl)amines and 1-(2,2-diphenylethyl)amines as condensation products in good yields (50-99%).

Reactions of amino alcohols in superacid: the direct observation of dicationic intermediates and their application in synthesis.

[reaction: see text]. The chemistry of amino alcohols has been studied in superacidic media, and these compounds have been found to ionize cleanly to the dication intermediates. Several dicationic species have been directly observed by low-temperature 13C NMR, including those from epinephrine (adrenaline) and synephrine. Amino alcohols react (70-99% yields) with C6H6 in triflic acid (CF3SO3H) by electrophilic aromatic substitution.

Anti-viral method

PCT No. PCT/US97/07431 Sec. 371 Date Jan. 6, 1999 Sec. 102(e) Date Jan. 6, 1999 PCT Filed May 2, 1997 PCT Pub. No. WO97/41846 PCT Pub. Date Nov. 13, 1997The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Urea, thiourea and guanidine compounds and their use as anti-viral agents

The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.