Amphocerin E, also known as amphotericin B, is a polyene antifungal medication derived from the fungus Streptomyces nodosus. It is widely used to treat systemic fungal infections, particularly those caused by Candida and Aspergillus species, which are resistant to other antifungal drugs. Amphotericin B works by binding to ergosterol, a component of fungal cell membranes, creating pores that disrupt the membrane's integrity, leading to cell death. Due to its broad-spectrum activity and efficacy against life-threatening fungal infections, it is considered a first-line treatment in severe cases. However, its use is often limited by potential side effects, such as nephrotoxicity and infusion-related reactions.
The CAS Registry Mumber 8038-67-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,3 and 8 respectively; the second part has 2 digits, 6 and 7 respectively. Calculate Digit Verification of CAS Registry Number 8038-67: (6*8)+(5*0)+(4*3)+(3*8)+(2*6)+(1*7)=103 103 % 10 = 3 So 8038-67-3 is a valid CAS Registry Number.