80403-84-5Relevant academic research and scientific papers
SYNTHESIS OF 3-HALOISOXAZOLES BY NOVEL OXIDATIVE DEGRADATION OF THE SIDE-CHAIN OF 3-(3-HALO-ISOXAZOL-5-YL) PROPIONIC ACIDS
Lugosi, Peter,Schawartz, Jozsef,Doleschall, Gabor
, p. 3061 - 3066 (2007/10/02)
A novel method for the oxidative degradation of the side-chain of 3-(3-haloisoxazol-5-yl) propionic acids has been developed.The E-3-(3-chloroisoxazol-5-yl) propenoic acid 13a obtained by treatment of the s-triazolo quinazolin-4-ium iodide 11a with PhI(OAc)2 and Bz2O2, respectively, and subsequent hydroxysis, has been used for the synthesis of numerous 3-haloisoxazole derivatives.
