80407-62-1Relevant academic research and scientific papers
Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase
Chowdhury, Shafinaz F.,Villamor, Victor Bernier,Guerrero, Ramon Hurtado,Leal, Isabel,Brun, Reto,Croft, Simon L.,Goodman, Jonathan M.,Maes, Louis,Ruiz-Perez, Luis M.,Pacanowska, Dolores Gonzalez,Gilbert, Ian H.
, p. 4300 - 4312 (2007/10/03)
This paper concerns the design, synthesis, and evaluation of inhibitors of leishmanial and trypanosomal dihydrofolate reductase. Initially study was made of the structures of the leishmanial and human enzyme active sites to see if there were significant d
