80418-27-5Relevant academic research and scientific papers
Tannins and Related Compounds. I. Rhubarb (1)
Nonaka, Gen-Ichiro,Nishioka, Itsuo,Nagasawa, Tetsuro,Oura, Hikokichi
, p. 2862 - 2870 (2007/10/02)
Three new tannin-related compounds (I, II and III), along with lindleyin (IV), (+)-catechin, 3-O-galloyl-(-)-epicatechin, gallic acid, 3,5,4'-trihydroxystilbene 4'-O-β-D-(6''-O-galloyl)-glucopyranoside, 3,5,4'-trihydroxystilbene 4'-O-β-D-glucopyranoside and 4-(4'-hydroxyphenyl)-2-butanone 4'-O-β-D-glucopyranoside, have been isolated from commercial rhubarb (Rhei Rhizoma).On the basis of spectral and chemical evidence, I, II and III were characterized as 3,3'-di-O-galloylprocyanidin B-2, 3-O-galloylprocyanidin B-1 and 1,2,6-tri-O-galloylglucose, respectively.The occurence of IV in rhubarb is of great significance, since IV has been reported to have analgesic and anti-inflammatory activities almost equal to those of aspirin and phenylbutanone.Tannins in rhubarb have been partially purified (designated as rhatannin (V)).Thiolysis degradation and enzymatic hydrolysis have shown that V is mainly composed of C4 to C8 linked 3-O-galloyl-(-)-epicatechin units in the extension part (upper part) with either 3-O-galloyl-(-)-epicatechin or (+)-catechin unit in the lower terminal part.Keywords. rhubarb; polygonaceae; 3,3'-di-O-galloylprocyanidin B-2; 3-O-galloylprocyanidin B-1; 1,2,6-tri-O-galloylglucose; lindleyin; rhatannin
