80418-47-9Relevant articles and documents
Chlorination of Esters. IV. Chlorination of Chloromethyl Esters of Aliphatic C3-C12 n-Carboxylic Acids. Determination of Monochloro Products by Gas-Liquid Chromatography and Gas-Liquid Chromatography-Mass Spectrometry
Korhonen, Ilpo O. O.
, p. 397 - 402 (2007/10/02)
The chlorinations with chlorine in the liquid phase at room temperature have been studied in the absence and in the presence of benzene.The products of ten substrates, 65 conmpounds altogether, were identified and estimated by gas-liquid chromatography (GLC) and gas-liquid chromatography-mass spectrometry (GLC-MS).The chlorinations yield all possible monochloro isomers, the (ω-1)-chloro isomers being in general the main products in the absence of benzene.The solvent alters the selectivity of the reagent, the main product varying from (ω-1)- to (ω-4)-chloro isomer with an increase in chain length.The amounts of ω-chloro isomers were 1.1-4.3 times greater in the absence of benzene.The isomeric monochloro chloromethyl esters are eluted in direct order from 2- to ω-chloro isomer on a Carbowax 20M glass capillary column.The 2-, 3-, 4-, 5- and ω-chloro isomers can be distinquished by mass spectrometry form the other isomers on the basis of characteristic fragment ions.The mass spectra of the mid-chain isomers were nearly similar to each other.
