80430-23-5Relevant academic research and scientific papers
Method and intermediates for preparing high purity 3,3'-azo-bis-(6-hydroxy benzoic acid)
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, (2008/06/13)
A method of preparing 3,3'-azo-bis-(6-hydroxy benzoic acid) of formula I STR1 and salts thereof in at least 98% purity for treating inflammatory intestinal diseases. According to the invention a compound II STR2 is diazotized, and the diazonium salt obtained is coupled with a compound III STR3 The formed intermediate IV, which is also comprised by the invention, STR4 is hydrolized in alkaline medium to form the compound I. R1, R2 and R3 signify lower alkyl, R2 also possibly substituted phenyl.
