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[D-PRO2, D-TRP7,9]-SUBSTANCE P is a modified form of the neuropeptide substance P, which plays a crucial role in pain perception and inflammation. The modification involves the substitution of proline at position 2 with D-proline and the substitution of tryptophan at positions 7 and 9 with D-tryptophan. This alteration results in enhanced stability and prolonged activity compared to the natural form, making it a promising candidate for various therapeutic applications.

80434-86-2

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80434-86-2 Usage

Uses

Used in Pharmaceutical Industry:
[D-PRO2, D-TRP7,9]-SUBSTANCE P is used as a therapeutic agent for the treatment of chronic pain and inflammatory conditions. Its enhanced stability and prolonged activity make it a potential alternative to conventional pain management medications, offering improved efficacy and reduced side effects.
Used in Neurological Research:
[D-PRO2, D-TRP7,9]-SUBSTANCE P is used as a research tool to study the modulation of neurogenic inflammation and nociception. Its ability to target specific pain pathways and receptors can provide valuable insights into the underlying mechanisms of pain perception and the development of novel pain management strategies.
Used in Psychiatry:
[D-PRO2, D-TRP7,9]-SUBSTANCE P is used as a potential modulator of mood and anxiety-related behaviors. Its influence on neurotransmitter systems and neural circuits involved in mood regulation and anxiety suggests that it could be a promising candidate for the development of new treatments for mood and anxiety disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 80434-86-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,4,3 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 80434-86:
(7*8)+(6*0)+(5*4)+(4*3)+(3*4)+(2*8)+(1*6)=122
122 % 10 = 2
So 80434-86-2 is a valid CAS Registry Number.
InChI:InChI=1/C74H106N20O13S/c1-42(2)36-55(66(100)85-51(63(79)97)30-35-108-3)89-68(102)58(39-45-41-84-50-22-10-8-19-47(45)50)92-67(101)56(37-43-16-5-4-6-17-43)90-69(103)57(38-44-40-83-49-21-9-7-18-46(44)49)91-65(99)52(26-28-61(77)95)86-64(98)53(27-29-62(78)96)87-70(104)60-25-15-34-94(60)73(107)54(23-11-12-31-75)88-71(105)59-24-14-33-93(59)72(106)48(76)20-13-32-82-74(80)81/h4-10,16-19,21-22,40-42,48,51-60,83-84H,11-15,20,23-39,75-76H2,1-3H3,(H2,77,95)(H2,78,96)(H2,79,97)(H,85,100)(H,86,98)(H,87,104)(H,88,105)(H,89,102)(H,90,103)(H,91,99)(H,92,101)(H4,80,81,82)/t48-,51-,52?,53-,54-,55?,56-,57+,58+,59+,60-/m0/s1

80434-86-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [D-PRO2, D-TRP7,9]-SUBSTANCE P

1.2 Other means of identification

Product number -
Other names 2-Pro-7,9-Trp-substance p

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80434-86-2 SDS

80434-86-2Upstream product

80434-86-2Downstream Products

80434-86-2Relevant academic research and scientific papers

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