Ulinastatin is a protease inhibitor drug that possesses anti-inflammatory, immunomodulatory, and anti-endotoxin properties. It is primarily utilized in the management of acute pancreatitis, sepsis, and other inflammatory conditions due to its ability to inhibit various proteases involved in the inflammatory response, such as trypsin, chymotrypsin, and elastase. Additionally, Ulinastatin has demonstrated the capacity to suppress the production of pro-inflammatory cytokines and mitigate the release of endotoxins, which are instrumental in triggering systemic inflammatory responses. Its potential in minimizing organ damage and enhancing outcomes for critically ill patients has been a subject of research. Administered intravenously, Ulinastatin is generally well-tolerated with minimal side effects.
80449-31-6
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Basic information
- Product Name: Ulinastatin
- Synonyms: URINASTATIN (UTI) SYN. BIKUNIN;D05183;Miraclid;Miraclid (tn);Ulinastatin (jp15);Purified Ulinastatin
- CAS NO:80449-31-6
- Molecular Formula: C13H16O3
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Ulinastatin(CAS DataBase Reference)
- NIST Chemistry Reference: Ulinastatin(80449-31-6)
- EPA Substance Registry System: Ulinastatin(80449-31-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 80449-31-6(Hazardous Substances Data)
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80449-31-6 Usage
Uses
Used in Pharmaceutical Industry:Ulinastatin is used as an anti-inflammatory and immunomodulatory agent for the treatment of acute pancreatitis, leveraging its ability to inhibit proteases and pro-inflammatory cytokines, thereby reducing inflammation and tissue damage.
Used in Critical Care Medicine:
In the critical care setting, Ulinastatin is employed as a therapeutic intervention for sepsis and other inflammatory conditions, where its anti-endotoxin effects help in managing the systemic inflammatory response and potentially improving patient outcomes.
Used in Research and Development:
Ulinastatin is utilized as a subject of study in research aimed at understanding its potential in reducing organ damage and enhancing recovery in critically ill patients, further expanding its applications in medical treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 80449-31-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,4,4 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.Calculate Digit Verification of CAS Registry Number 80449-31:
(7*8)+(6*0)+(5*4)+(4*4)+(3*9)+(2*3)+(1*1)=126
126 % 10 = 6
So 80449-31-6 is a valid CAS Registry Number.
80449-31-6Upstream product
80449-31-6Downstream Products
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Ulinastatin
