804518-91-0

Upstream product

• 319-61-9 (S)-1-(trifluoroacetyl)pyrrolidine-2-carboxylic acid 
• 804519-39-9 2,2,2-Trifluoro-1-[(S)-2-(4-methoxy-benzoyl)-pyrrolidin-1-yl]-ethanone 
• 804519-44-6 (S)-2-(4-Methoxy-benzyl)-pyrrolidine 
• 198226-53-8 2-chloro-6-([(2R)-2-oxiranylmethyl]oxy)benzonitrile 
• 89999-90-6 3-chloro-2-cyanophenol 
• 848073-19-8 C₁₉H₁₇F₃NO₄P 

Relevant academic research and scientific papers

Discovery and structure-activity relationships of 2-benzylpyrrolidine- substituted aryloxypropanols as calcium-sensing receptor antagonists

A structure-activity relationship study of the amine portion of the calcilytic compound NPS-2143 resulted in the discovery of substituted 2-benzylpyrrolidines as replacements for the 1,1-dimethyl-2-naphthalen-2-yl- ethylamine. When compared to NPS-2143, a

SUBSTITUTED PIPERODINES AND PYRROLIDINES AS CALCIUM SENSING RECEPTOR MODULATORS AND METHOD

Compounds are provided which are antagonists of the calcium sensing receptor, and have the general formula (I) wherein m is 0, 1, 2, 3 or 4; each X is independently selected from the group consisting of hydrogen, halo, cyano, nitro, OCF3, hydroxy, amino,