80452-02-4

Upstream product

• 55301-13-8 Boc-Gly-Pro-Gly-OBzl 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 63496-06-0 L-prolylglycine benzyl ester 
• 31953-80-7 N-tert-butyloxycarbonyl-(2S)-prolyl-glycine benzyl ester 

Downstream Products

• 80451-92-9 Boc-Leu-Gly-Gly-Gly-Pro-Gly-OBzl 
• 219575-90-3 Boc-Arg(Tos)-Ile-Gln-Arg(Tos)-Gly-Pro-Gly(OBzl) 

Relevant academic research and scientific papers

Synthesis of Tn, sialyl Tn and HIV-1-derived peptide antigen conjugates having a lipid a analog as an immunoadjuvant for synthetic vaccines

Conjugates (3-5) of Tn, sialyl Tn and HIV-1-derived peptide antigen with a N-tetradecanoyl L-serine-β-alanine-containing D-glucosamine derivative, structurally related to lipid A, as an immunoadjuvant for the development of totally synthetic vaccines against cancers or HIV were synthesized. The mitogenic activity of compounds 3, 4 and 5 was stronger than that of lipid A analogs (1, 2).