804531-65-5Relevant academic research and scientific papers
Optimization of the catalytic asymmetric addition of nitroalkanes to cyclic enones with trans-4,5-methano-L-proline
Hanessian, Stephen,Shao, Zhihui,Warrier, Jayakumar S.
, p. 4787 - 4790 (2006)
(Chemical Equation Presented) The conjugate addition of symmetrical 2-nitroalkanes to 2-cycloalkenones catalyzed by trans-4,5-methano-L-proline proceeds with >99% ee and excellent chemical yields. 1-Nitroalkanes afford diastereomeric syn/anti products tha
Synthesis and evaluation of guanidinyl pyrrolidines as bifunctional catalysts for enantioselective conjugate additions to cyclic enones
Pansare, Sunil V.,Lingampally, Rajinikanth
supporting information; experimental part, p. 319 - 324 (2009/03/12)
Guanidinyl pyrrolidines derived from 'S'-proline are effective catalysts for the enantioselective conjugate addition of malonate, nitroalkane and other carbon and heteroatom nucleophiles to cyclohexenone and cyclopentenone in the absence of basic additive
An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones
Mitchell, Claire E. T.,Brenner, Stacey E.,Garcia-Fortanet, Jorge,Ley, Steven V.
, p. 2039 - 2049 (2008/02/05)
5-Pyrrolidin-2-yltetrazole is a versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones. Using this catalyst, this transformation requires short reaction times, tolerates a broad substrate scope, and possibly proceeds via
A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones
Mitchell, Claire E. T.,Brenner, Stacey E.,Ley, Steven V.
, p. 5346 - 5348 (2007/10/03)
5-Pyrrolidin-2-yltetrazole performs as an improved catalyst for the asymmetric addition of a range of nitroalkanes to cyclic and acyclic enones, with good to excellent enantioselectivity. The Royal Society of Chemistry 2005.
Trends in asymmetric Michael reactions catalysed by tripeptides in combination with an achiral additive in different solvents
Tsogoeva, Svetlana B.,Jagtap, Sunil B.,Ardemasova, Zoya A.,Kalikhevich, Victor N.
, p. 4014 - 4019 (2007/10/03)
The potential of tripeptides 3, 6 and 12 as chiral catalysts for asymmetric Michael addition reactions in the presence of an achiral additive has been tested in different solvents (CHCI3, acetone, DMF, DMSO and the room-temperature ionic liquid
Catalytic asymmetric conjugate addition of nitroalkanes to cycloalkenones
Hanessian, Stephen,Pham, Vinh
, p. 2975 - 2978 (2007/10/03)
Nitroalkanes add to cyclic and acyclic enones in an enantioselective manner in the presence of catalytic quantities of L-proline and trans2,5-dimethylpiperazine as excess additive.
