804548-60-5

Basic information

• Product Name: 2(3H)-Furanone, 4-[8-[[(1,1-dimethylethyl)diphenylsilyl]oxy]octyl]dihydro-5-[[(1R,2S,5R)-5- methyl-2-(1-methylethyl)cyclohexyl]oxy]-, (4R,5S)-
• CAS NO: 804548-60-5
• Molecular Formula: C38H58O4Si
• Molecular Weight: 606.962
• Mol File: 804548-60-5.mol

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone, 4-[8-[[(1,1-dimethylethyl)diphenylsilyl]oxy]octyl]dihydro-5-[[(1R,2S,5R)-5- methyl-2-(1-methylethyl)cyclohexyl]oxy]-, (4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, 4-[8-[[(1,1-dimethylethyl)diphenylsilyl]oxy]octyl]dihydro-5-[[(1R,2S,5R)-5- methyl-2-(1-methylethyl)cyclohexyl]oxy]-, (4R,5S)-(804548-60-5)
• EPA Substance Registry System: 2(3H)-Furanone, 4-[8-[[(1,1-dimethylethyl)diphenylsilyl]oxy]octyl]dihydro-5-[[(1R,2S,5R)-5- methyl-2-(1-methylethyl)cyclohexyl]oxy]-, (4R,5S)-(804548-60-5)

Safety Data

• Hazardous Substances Data: 804548-60-5(Hazardous Substances Data)

Upstream product

• 112968-75-9 (5R)-(L-menthyloxy)-2(5H)-furanone 
• 144487-53-6 8-iodo-1-(tert-butyldiphenylsilyloxy)-octane 

Relevant articles and documents

Conjugate addition of organocopper reagents to γ-alkoxybutenolides and application to the synthesis of non-racemic alkyl cyclopentenones

Simple organocopper reagents are shown to undergo anti-stereoselective 1,4-addition to menthyloxy-substituted lactone 1 in the presence of BF 3·OEt2; the Lewis acid causes partial epimerisation of the acetal centre after conjugate addition. Enolate alkylation of the adducts leads to di- and trisubstituted lactones that are converted, in favourable cases, into di- and trisubstituted cyclopentenones.