804553-24-0

Upstream product

• 2717-44-4 2-methyl-3,4-dihydronaphthalene 
• 598-32-3 2-hydroxy-3-butene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 1574475-07-2 C₁₄H₂₁NO₄ 
• 1574475-06-1 C₁₄H₂₀O₄ 
• 86867-62-1 (E)-3-(2-formylphenyl)propenoic acid ethyl ester 

Downstream Products

• 1574474-98-8 C₁₅H₂₁NO₂S 

Relevant academic research and scientific papers

Asymmetric synthesis of novel vicinal amino alcohols via intramolecular ketone- N -sulfinylimine pinacol-type reductive coupling promoted by SmI 2

A novel intramolecular asymmetric ketone-N-sulfinylimine pinacol-type reductive coupling reaction induced by SmI2 was reported. A series of 1-amino-1,2,3,4-tetrahydronaphthalen-2-carbinols were obtained in moderate to good yields with excellent

Studies on the synthesis of 2-acyl-1H-indenes via one-pot palladium-catalysed tandem Heck-aldol reaction

2-Acyl-1H-indenes were synthesised efficiently by the reaction of o-halogenatedbenzaldehydes (or aryl ketones) with prop-2-en-1-ols via one-pot palladium-catalysed tandem Heck-aldol reaction in moderate to good yields. The optimal reaction conditions have

Thiazolium ylide-catalyzed intramolecular aldehyde-ketone benzoin-forming reactions: Substrate scope

The scope and limitations of intramolecular benzoin-forming reactions of aldehydes and ketones catalyzed by the combination of a thiazolium salt and a base are described. After optimization of the reaction conditions, five- and six-membered cyclic acyloins were obtained in good to excellent yields and competing reactions such as intramolecular aldol reactions were suppressed. The analogous closure of seven-membered rings proved difficult.

Thiazol-2-ylidene catalysis in intramolecular crossed aldehyde-ketone benzoin reactions

Intramolecular crossed aldehyde-ketone benzoin-type reactions catalyzed by nucleophilic carbenes, easily generated from commercially available thiazolium salts as precatalysts, are described. Five- and six-membered cyclic acyloins are obtained in moderate to good yields. Depending on the structure of the aldehyde-ketone substrate, an interchange of the alcohol and ketone function of the resulting acyloin is possible. Simple aldehyde-ketones are not good substrates due to the competing intermolecular reaction. Starting from biphenyl-2,2′-dicarbaldehyde, the intermediate acyloin is converted to 9,10-phenanthrenequinone by mild air oxidation.