80478-01-9

Basic information

• Product Name: 1,3-diacetyl-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one
• Synonyms: 1,3-diacetyl-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one
• CAS NO: 80478-01-9
• Molecular Weight: 308.337
• Mol File: 80478-01-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-diacetyl-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-diacetyl-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one(80478-01-9)
• EPA Substance Registry System: 1,3-diacetyl-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one(80478-01-9)

Safety Data

• Hazardous Substances Data: 80478-01-9(Hazardous Substances Data)

Upstream product

• 121998-76-3 2-phenyl-2,3-dihydro-4(1H)-quinazolinone 
• 108-24-7 acetic anhydride 

Relevant articles and documents

REACTION OF 1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONES WITH ACID ANHYDRIDE. II

The reaction of 1,2,3,4-tetrahydroquinazoline-2-spirocyclohexan-4-one (1b) with acetic anhydride and pyridine gave 1-(1-cyclohexenyl)-2-methyl-1,4-dihydroquinazolin-4-one (3b).Compound 3b gave 3-acetyl-1-(1-cyclohexenyl)-2-methyl-1,2,3,4-tetrahydroquinazolin-4-one (8b) upon reduction with NaBH4 followed by acetylation with acetic anhydride.The position of the acetyl group of 8b was determined by comparison of its NMR spectrum with those of related compounds (9, 10, 11, 12, and 13).Keywords: 4-quinazoline; acetylation; rearrangement; 1H-NMR; spiro compound