80478-10-0

Upstream product

• 106-49-0 p-toluidine 
• 61885-26-5 6-bromomethyl-1,3-dimethyl-5-nitrouracil 

Downstream Products

• 80478-06-4 5-Amino-1,3-dimethyl-6-(p-tolylamino-methyl)-1H-pyrimidine-2,4-dione 
• 81649-73-2 4,6-Dimethyl-1-oxy-2-p-tolyl-2,4-dihydro-pyrazolo[4,3-d]pyrimidine-5,7-dione 
• 80478-17-7 1,3-Dimethyl-7-p-tolyl-7,8-dihydro-1H-pyrimido[5,4-d]pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Pyrimidine Derivatives and Related Compounds. Part 41. Reactions of 1,3,6-Trimethyl-5-nitrouracil and its 6-Bromomethyl Analogue with Amines and Hydrazines. Synthesis of Pyrazolopyrimidine N-Oxides and their Ring Expansion to Pyrimidopyrimid

Reactions of 1,3,6-trimethyl-5-nitrouracil (1) and 6-bromomethyl-1,3-dimethyl-5-nitrouracil (4) with amines and hydrazines have been studied with the aim of synthesising fused-ring pyrimidines.Treatment of compound (4) with primary amines afforded 2-subst