80482-76-4Relevant articles and documents
HIPPURISTANOLS, CYTOTOXIC POLYOXYGENATED STEROIDS FROM THE GORGONIAN ISIS HIPPURIS
Higa, Tatsuo,Tanaka, Jun-ichi,Tsukitani, Yasumasa,Kikuchi, Hiroyuki
, p. 1647 - 1650 (1981)
Four new polyoxygenated steroids (4-7) containing a spiroketal function have been isolated from the gorgonian Isis hippuris.Their structures were determined by spectral correlation and by interconversion.Previously assigned configuration at the C-22 of hippurin-1 (3) was reversed by spectroscopic evidence.Two (4,7) of the steroids exhibited potent in vitro anticancer activities.