80487-52-1

Upstream product

• 82505-79-1 4-<4-(Trimethylstannyl)-1,3-butadiinyl>morpholin 
• 80487-51-0 C₈H₈LiNO 
• 60014-60-0 N-(3,4,4-Trichlor-3-buten-1-inyl)morpholin 
• 13178-29-5 N-(Pentachlor-1,3-butadienyl)morpholin 

Downstream Products

• 135703-38-7 3-(4-Methoxyphenyl)-5-morpholino-4-<3-(4-nitrophenyl)-5-isoxazolyl>isoxazol 
• 135703-40-1 4-<3-(4-Methoxyphenyl)-5-isoxazolyl>-5-morpholino-3-(4-nitrophenyl)isoxazol 
• 135703-37-6 3-(4-Methoxyphenyl)-5-morpholino-4-(3-phenyl-5-isoxazolyl)isoxazol 
• 135703-39-8 4-<3-(4-Methoxyphenyl)-5-isoxazolyl>-5-morpholino-3-phenyl-isoxazol 
• 135703-35-4 3-(4-Methoxyphenyl)-4-<3-(4-methoxyphenyl)-5-isoxazolyl>-5-morpholino-isoxazol 
• 135703-17-2 3-(4-Methoxyphenyl)-5-(morpholinoethinyl)isoxazol 
• 135703-33-2 5-Morpholino-3-(4-nitrophenyl)-4-<3-(4-nitrophenyl)-5-isoxazolyl>isoxazol 
• 135703-16-1 5-(Morpholinoethinyl)-3-(4-nitrophenyl)isoxazol 
• 135703-34-3 3-Mesityl-4-(3-mesityl-5-isoxazolyl)-5-morpholino-isoxazol 
• 135703-36-5 5-Morpholino-3-phenyl-4-(3-phenyl-5-isoxazolyl)isoxazol 
• 135703-15-0 5-(Morpholinoethinyl)-3-phenylisoxazol 
• 113568-35-7 N-Methyl-N-(7,8,8-trichlor-7-octen-1,3,5-triinyl)anilin 

Relevant academic research and scientific papers

Polyynes, 3. - Synthesis of (1,3-Alkadiylnyl)amines

By the reaction of (3,4,4-trichloro-3-buten-1-ynyl)amines 2 or of (pentachloro-1,3-butadienyl)-amines 4 with the twofold or threefold equimolar amount of butyllithium the corresponding lithium 4-amino-1,3-butadiynides 5 are prepared.These compounds yield

157. Synthese von 'Push-Pull'-Diacetylenen

The first synthesis of push-pull diacetylenes of type 1 is described.Reaction of perchlorobutyne (8) with two equivalents of dialkylamine, followed by dechlorination using two equivalents of butyllithium gives lithio-dialkylamino-diynes 7.Final acylation of these intermediates leads to push-pull diacetylenes 1b-1e in good yields.The method allows the introduction of both push and pull substituents in a simple one-pot-procedure.In addition, 1a is prepared by hydroxymethylation of lithio-morpholino-diyne 7c, followed by oxidation with manganese dioxide in acetone.