80491-23-2Relevant academic research and scientific papers
Coupled Flavin-Iodine Redox Organocatalysts: Aerobic Oxidative Transformation from N-Tosylhydrazones to 1,2,3-Thiadiazoles
Ishikawa, Tatsuro,Kimura, Maasa,Kumoi, Takuma,Iida, Hiroki
, p. 4986 - 4989 (2017/08/17)
A bioinspired two-component redox organocatalyst system using 1,10-bridged flavinium and NH4I was developed to perform environmentally friendly aerobic oxidative ring formation of 1,2,3-thiadiazoles from N-tosylhydrazones and sulfur. The redox
THE REACTION OF α,β-UNSATURATED p-TOSYLHYDRAZONES WITH SULPHUR CHLORIDES
Bellesia, Franco,Grandi, Romano,Pagnoni, Ugo M.,Trave, Roberto
, p. 289 - 292 (2007/10/02)
α,β-Unsaturated p-tosylhydrazones react with tetravalent and divalent sulphur chlorides affording 1,2,3-thiadiazoles in good yields.The necessary methylene group adjacent to the C=N bond may be provided by electrophilic addition of a hydrogen chloride molecule.The major difference in the product distribution in the reactions of unsaturated and saturated p-tosylhydrazones with SOCl2, SCl2 or S2Cl2 is observed with substrates prepared from methyl ketones; on using SOCl2 a more favourable distribution of compounds derived from cyclization on the methyl group is obtained.
