80491-49-2

Upstream product

• 63905-25-9 2-hydroxy-3-(2-aminophenoxy)propanol 
• 61396-67-6 rac-3-(2-nitrophenoxy)-1,2-propanediol 
• 88-75-5 2-hydroxynitrobenzene 
• 614-80-2 2-(acetylamino)phenol 
• 63905-15-7 N-(2-(2,3-dihydroxypropoxy)phenyl)acetamide 

Downstream Products

• 80491-47-0 N-Chloroacetyl-o-aminophenylglycerylether 
• 80491-48-1 N-(3-Chloropropanoyl)-o-aminophenylglycerylether 
• 80491-61-8 N-(i-Propylaminoacetyl)-o-aminophenylglycerylether 
• 80491-60-7 N-(t-Butylaminoacetyl)-o-aminophenylglycerylether 
• 80491-51-6 N-Piperidinoacetyl-o-aminophenylglycerylether 
• 80491-59-4 N-Morpholinoacetyl-o-aminophenylglycerylether 
• 80491-57-2 N--o-aminophenylglycerylether 
• 80491-54-9 N-(4-Phenylpiperidinoacetyl)-o-aminophenylglycerylether 
• 80491-56-1 N-(N-Phenylpiperazinoacetyl)-o-aminophenylglycerylether 
• 80491-53-8 N-(4-Hydroxy-4-phenylpiperidinoacetyl)-o-aminophenylglycerylether 
• 80491-55-0 N--o-aminophenylglycerylether 
• 80491-50-5 N-Dimethylaminoacetyl-o-aminophenylglycerylether Hydrochloride 
• 80491-52-7 N-Diethylaminoacetyl-o-aminophenylglycerylether Hydrochloride 
• 80491-58-3 Bispiperazine 

Relevant academic research and scientific papers

Polyaniline copolymers with solvent-mimic side chains

We investigated new polyaniline copolymers with solvent-mimic side chains for enhanced processability in various solvents. The solvent-mimic side chains, benzyloxypropoxy (BOP), phenoxybutoxy (POB), and dihydroxypropoxy (DHP), were introduced into copolym

Synthesis and aminopeptidase n inhibiting activity of 3-(nitrophenoxymethyl)-[1,3,2]dioxaborolan-2-OLS and their open analogues

Aminopeptidase N (APN) represents a class of zinc metallopeptidases with broad substrate specifity. This enzyme is involved in control of angioneogenesis in cancer and microvascular conditions. It also serves as a superficial cellular receptor that enables attachment of some viruses including coronaviruses to the host cell. APN takes part also in metabolism of some important neuropeptides. That is why APN can be a promising therapeutic target and compounds which influence its activity interesting potential drugs. Here, synthesis of compounds which in most contain 3-phenoxypropan-1,2 diol moiety and evaluation of their inhibition activity against APN is described. 4-[1-, 2- and 3-(Nitrophenoxymethyl)]-[1,3,2]dioxaborolan-2-ols are novel compounds which have never been previously reported in the literature. 3-(Aminophenoxy)propyl-1,2-diols revealed greater activity than both 3-(nitrophenoxy)propyl-1,2-diols and 3-(nitrophenoxymethyl)-[1,3,2]dioxaborolan-2-ols. A QSAR study revealed a linear correlation between lipophilicity and inhibition activity.