80494-97-9Relevant academic research and scientific papers
Synthesis and Neuroleptic Activity of N--2-methoxy-5-sulfonamidobenzamides
Ogata, Masaru,Matsumoto, Hiroshi,Kida, Shiro,Shiomi, Teruo,Eigyo, Masami,Hirose, Katsumi
, p. 1137 - 1141 (2007/10/02)
A series of some novel N-benzamides involving replacement of the sulfamoyl group in sulpiride with a sulfonamido group was synthesized and tested for dopamine receptor blockade.In comparison with sulpiride, several compounds were considerably more potent than sulpiride as dopamine receptor blockers.The structure-activity relationships are discussed.
