805-84-5

Basic information

• Product Name: methylenedehydroacetoxyprogesterone
• Synonyms: methylenedehydroacetoxyprogesterone
• CAS NO: 805-84-5
• Molecular Formula: C24H30O4
• Molecular Weight: 382.4926
• Mol File: 805-84-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 513.6°C at 760 mmHg
• Flash Point: 221.9°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 1.16E-10mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: methylenedehydroacetoxyprogesterone(CAS DataBase Reference)
• NIST Chemistry Reference: methylenedehydroacetoxyprogesterone(805-84-5)
• EPA Substance Registry System: methylenedehydroacetoxyprogesterone(805-84-5)

Safety Data

• Hazardous Substances Data: 805-84-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C24H30O4/c1-14-12-21-19-7-6-17-13-18(27)8-10-22(17,4)20(19)9-11-23(21,5)24(14,15(2)25)28-16(3)26/h6-7,13,19-21H,1,8-12H2,2-5H3/t19-,20+,21+,22+,23+,24+/m1/s1

Upstream product

• 10087-46-4 17α-Acetoxy-16-methylen-progesteron-enol-(3)-ethylether 
• 6815-51-6 17α-Acetoxy-16-methylen-Δ⁴-pregnenol-(17α)-dion-(3,20) 
• 6757-13-7 17α-Acetoxy-3,20-dioxo-6β-brom-16-methylen-pregnen-4 
• 108-24-7 acetic anhydride 
• 10087-53-3 6β-Chlor-16α.17α-epoxy-3.20-dioxo-16β-methyl-pregnen-(4) 
• 6891-67-4 6β-Chlor-16-methylen-17α-acetoxy-pregnen-(4)-dion-(3,20) 

Relevant articles and documents

Synthesis and biological activity of 17-esters of 6-dehydro-16-methylene-17 -hydroxyprogesterones.

Synthesis and biological activity of 17-esters of 6-dehydro-16-methylene-17 alpha-hydroxyprogesterone are presented. A systematic study of the influence of the alteration of halogen at 6 and the acyl group at 17 on the progestational and antiandrogenic activities of the resulting structures is described. A convenient general method for synthesis of all of the members of the generic family from the precursors in common is described. It is believed that 6-chloro-16-methylene-17 alpha-hydroxy-4,6-pregnadiene 17-acetate, because of its structural similarity to chlormadinone acetate and its high progestational potency, will perform as a contraceptive at perhaps a lower dose than that of chlormadinone acetate.