Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus. It is known for its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, as well as some fungi. The antibiotic works by inhibiting protein synthesis in bacteria, which is achieved by binding to the 30S ribosomal subunit and causing misreading of the genetic code. This leads to the production of nonfunctional proteins, ultimately resulting in bacterial cell death. Hygromycin B is used in various applications, including agriculture as a selective agent in genetic engineering to identify transformed cells, and in the pharmaceutical industry for the production of recombinant proteins. It is also used in veterinary medicine to treat certain bacterial infections in animals. Due to its potential for resistance development and side effects, its use in human medicine is limited.
The CAS Registry Mumber 8052-93-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,5 and 2 respectively; the second part has 2 digits, 9 and 3 respectively. Calculate Digit Verification of CAS Registry Number 8052-93: (6*8)+(5*0)+(4*5)+(3*2)+(2*9)+(1*3)=95 95 % 10 = 5 So 8052-93-5 is a valid CAS Registry Number.