80522-46-9

Basic information

• Product Name: Silane, (1-cyclohexen-1-yloxy)tris(1-methylethyl)-
• CAS NO: 80522-46-9
• Molecular Formula: C15H30OSi
• Molecular Weight: 254.488
• Mol File: 80522-46-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Silane, (1-cyclohexen-1-yloxy)tris(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1-cyclohexen-1-yloxy)tris(1-methylethyl)-(80522-46-9)
• EPA Substance Registry System: Silane, (1-cyclohexen-1-yloxy)tris(1-methylethyl)-(80522-46-9)

Safety Data

• Hazardous Substances Data: 80522-46-9(Hazardous Substances Data)

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 108-94-1 cyclohexanone 
• 6485-79-6 chlorotriisopropylsilane 
• 930-68-7 cyclohexenone 
• 13154-24-0 triisopropylsilyl chloride 
• 213339-58-3 C₁₁H₂₁F₆NO₄S₂Si 

Downstream Products

• 56734-76-0 α-tridecafluorohexylcyclohexanone 
• 132091-45-3 2-Perfluorohexyl-1-triisopropylsiloxy-1-cyclohexene 
• 132111-67-2 6-Perfluorohexyl-1-triisopropylsiloxy-1-cyclohexene 
• 144810-05-9 Triisopropyl-(2-phenylsulfanyl-cyclohex-1-enyloxy)-silane 
• 144810-06-0 Triisopropyl-(6-phenylsulfanyl-cyclohex-1-enyloxy)-silane 
• 747-58-0 9,10-diphenyl-1,2,3,4,9,10-hexahydro-9,10-epoxyanthracene 
• 105-60-2 caprolactam 

Relevant articles and documents

One-Pot Synthesis of Silylated Enol Triflates from Silyl Enol Ethers for Cyclohexynes and 1,2-Cyclohexadienes

Regiocontrolled synthesis of precursors for strained cyclohexynes and 1,2-cyclohexadienes is described based on one-pot rearrangement of silyl enol ether followed by formation of enol triflate. Treatment of silyl enol ether with a combination of LDA and tBuOK led to the migration of the silyl group to generate α-silyl enolate, which was treated with Comins' reagent to provide the corresponding enol triflate. The transient α-silylated lithium enolate was smoothly isomerized in the presence of stoichiometric amount of water within one hour at room temperature, providing precursors for cyclohexynes exclusively in one pot. Effects of silyl groups, isomerization of the lithium enolate, and regiocontrolled generation of these precursors for these strained molecules were also investigated.

Catalytic [3+2] annulation of aminocyclopropanes for the enantiospecific synthesis of cyclopentylamines

With nitrogen too: The first catalytic [3+2] annulation of aminocyclopropanes with enol ethers is reported (see scheme; Phth=phthaloyl). The reaction worked with easily accessible phthalimidocyclopropanes using 5 mol % of SnCl4 in nearly quantitative yields. Polysubstituted cyclopentylamines, which are often present in bioactive compounds, were obtained with high diastereoselectivity and enantiospecificity. Copyright

Pd(OH)2/C-mediated selective oxidation of silyl enol ethers by tert-butylhydroperoxide, a useful method for the conversion of ketones to α,β-enones or β-Silyloxy-α,β-enones

(Chemical Equation Presented) Pd(OH)2-catalyzed oxidation of silyl enol ethers by t-BuOOH gives either β-silyloxy-α,β-enones or α,β-enones in good yields depending on the base used.