805227-72-9Relevant academic research and scientific papers
Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates
Crucianelli, Marcello,De Angelis, Francesco,Lazzaro, Francesco,Malpezzi, Luciana,Volonterio, Alessandro,Zanda, Matteo
, p. 573 - 577 (2007/10/03)
We describe the first synthesis of enantiomerically pure (S)-α-vinyl and (S)-α-ethynyl 3,3,3-trifluoro alanine (TF-Ala) ethyl esters, starting from the in situ generated sulfinimine (S)-2 as key fluorinated building-block. (S)-α-Ethyl TF-Ala-OEt has been prepared as well by this route.
