805246-48-4Relevant academic research and scientific papers
Asymmetric synthesis of 3-substituted proline chimeras bearing polar side chains of proteinogenic amino acids
Quancard, Jean,Labonne, Aurelie,Jacquot, Yves,Chassaing, Gerard,Lavielle, Solange,Karoyan, Philippe
, p. 7940 - 7948 (2007/10/03)
The amino-zinc-ene-enolate cyclization reaction is a straightforward route to the synthesis of 3-substituted prolines. Herein we report the application of this reaction to the syntheses of proline chimeras of lysine, glutamic acid, glutamine, arginine, an
