80525-79-7

Basic information

• Product Name: 4-[(2H-pyrrol-2-ylidenemethyl)amino]benzoic acid
• CAS NO: 80525-79-7
• Molecular Formula: C₁₂H₁₀N₂O₂
• Molecular Weight: 214.22
• Mol File: 80525-79-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 407.9°C at 760 mmHg
• Flash Point: 200.5°C
• Density: 1.24g/cm³
• Vapor Pressure: 2.19E-07mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 4-[(2H-pyrrol-2-ylidenemethyl)amino]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(2H-pyrrol-2-ylidenemethyl)amino]benzoic acid(80525-79-7)
• EPA Substance Registry System: 4-[(2H-pyrrol-2-ylidenemethyl)amino]benzoic acid(80525-79-7)

Safety Data

• Hazardous Substances Data: 80525-79-7(Hazardous Substances Data)

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 150-13-0 4-amino-benzoic acid 

Relevant articles and documents

The synthesis of novel methotrexate-like compounds

Methotrexate (MTX) is a folate antagonist used in treatment of several chronic inflammatory and neoplastic conditions. In this study, new MTX-like compounds that may-be potential anticancer agents were synthesized and their structures were determined by IR, UV, GC-MS, 1H NMR, and 13C NMR spectra. Also, in this study, a series structurally related to MTX or folate analogous compounds were evaluated whether they have inhibitory properties on the dihydrofolate reductase activity (DHFR).