Welcome to LookChem.com Sign In|Join Free

CAS

  • or

80531-13-1

Post Buying Request

80531-13-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

80531-13-1 Usage

General Description

1-benzyl-1H-indole-5-carbonitrile is an organic compound with the molecular formula C18H14N2. It is a benzyl-substituted indole derivative, and its chemical structure features a benzene ring attached to a nitrogen-containing indole ring with a cyano group at the 5-position. 1-benzyl-1H-indole-5-carbonitrile is commonly used as a building block in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. It also exhibits biological activity and may have potential applications in medicinal chemistry. Additionally, 1-benzyl-1H-indole-5-carbonitrile is known for its photoluminescent properties, and it has been studied as a fluorescent probe for detecting certain biological molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 80531-13-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,3 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 80531-13:
(7*8)+(6*0)+(5*5)+(4*3)+(3*1)+(2*1)+(1*3)=101
101 % 10 = 1
So 80531-13-1 is a valid CAS Registry Number.

80531-13-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-benzylindole-5-carbonitrile

1.2 Other means of identification

Product number -
Other names 1-BENZYL-1H-INDOLE-5-CARBONITRILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80531-13-1 SDS

80531-13-1Relevant articles and documents

Transition-Metal-Free and Base-Promoted Carbon-Heteroatom Bond Formation via C-N Cleavage of Benzyl Ammonium Salts

Liu, Long,Tang, Yuanyuan,Wang, Kunyu,Huang, Tianzeng,Chen, Tieqiao

, p. 4159 - 4170 (2021/03/09)

A facile and general method for constructing carbon-heteroatom (C-P, C-O, C-S, and C-N) bonds via C-N cleavage of benzyl ammonium salts under transition-metal-free conditions was reported. The combination of t-BuOK and 18-crown-6 enabled a wide range of substituted benzyl ammonium salts to couple readily with different kinds of heteroatom nucleophiles, i.e. hydrogen phosphoryl compounds, alcohols, thiols, and amines. Good functional group tolerance was demonstrated. The scale-up reaction and one-pot synthesis were also successfully performed.

The palladium-catalyzed direct C3-cyanation of indoles using acetonitrile as the cyanide source

Feng, Kejun,Li, Qiang,Li, Yuanhua,Liu, Bifu,Liu, Min,Zhou, Yongbo

supporting information, p. 6108 - 6114 (2020/10/21)

The ligand-free palladium-catalyzed C3-cyanation of indoles via direct C-H functionalization was achieved. This protocol, utilizing CH3CN as a green and readily available cyanide source, produced the desired products in moderate to good yields through transition-metal-catalyzed C-CN bond cleavage. This journal is

General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves

Sun, Nan,Hong, Lingfen,Huang, Fang,Ren, Hong,Mo, Weimin,Hu, Baoxiang,Shen, Zhenlu,Hu, Xinquan

, p. 3927 - 3933 (2013/06/27)

A general and efficient method for the synthesis of 2,3-unsubstituted indoles has been established by the intramolecular cyclization of N-benzyl 2-anilinoacetals. Acidic mesoporous molecular sieve (MCM-41-SO3H) has shown excellent catalytic activity on this transformation, and the 2,3-unsubstituted indoles bearing 7-substituent or strong electron-withdrawing substituents also could be achieved by this protocol. Moreover, the heterogeneous catalyst, MCM-41-SO3H, could be conveniently recovered and reused without obvious loss of the catalytic activity. This work will provide an economic and environmental-benign method for the construction of various indole derivatives.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 80531-13-1