Welcome to LookChem.com Sign In|Join Free
  • or
2-Bromo-5-chloro-8-methyl-8H-imidazo[4,5-d]thiazole[5,4-b]pyridine is a complex organic chemical compound with the molecular formula C9H6BrClN3S. It is characterized by the presence of a 2-bromo and 5-chloro substituent on the imidazothiazole ring, as well as an 8-methyl group. 2-BROMO-5-CHLORO-8-METHYL-8H-IMIDAZO[4,5-D]THIAZOLO[5,4-B]PYRIDINE is a member of the imidazothiazole class of chemicals, which are known for their diverse range of biological activities and potential applications in pharmaceuticals and materials science. The specific structure of 2-BROMO-5-CHLORO-8-METHYL-8H-IMIDAZO[4,5-D]THIAZOLO[5,4-B]PYRIDINE, with its unique combination of halogens and a methyl group, may confer particular properties that could be of interest in various chemical or biological contexts.

805319-85-1

Post Buying Request

805319-85-1 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

805319-85-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 805319-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,5,3,1 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 805319-85:
(8*8)+(7*0)+(6*5)+(5*3)+(4*1)+(3*9)+(2*8)+(1*5)=161
161 % 10 = 1
So 805319-85-1 is a valid CAS Registry Number.

805319-85-1Relevant academic research and scientific papers

Novel tricyclic inhibitors of 1κB kinase

Kempson, James,Spergel, Steven H.,Guo, Junqing,Quesnelle, Claude,Gill, Patrice,Belanger, Dominique,Dyckman, Alaric J.,Li, Tianle,Watterson, Scott H.,Langevine, Charles M.,Das, Jagabandhu,Moquin, Robert V.,Furch, Joseph A.,Marinier, Anne,Dodier, Marco,Martel, Alain,Nirschl, David,Van Kirk, Katy,Burke, James R.,Pattoli, Mark A.,Gillooly, Kathleen,McIntyre, Kim W.,Laishun, Chen,Zheng, Yang,Marathe, Punit H.,Wang-Iverson, David,Dodd, John H.,McKinnon, Murray,Barrish, Joel C.,Pitts, William J.

experimental part, p. 1994 - 2005 (2009/12/31)

The design and synthesis of a novel series of oxazole-, thiazole-, and imidazole-based inhibitors of IκB kinase (IKK) are reported. Biological activity was improved compared to the pyrazolopurine lead, and the expedient synthesis of the new tricyclic systems allowed for efficient exploration of structure-activity relationships. This, combined with an iterative rat cassette dosing strategy, was used to identify compounds with improved pharmacokinetic (PK) profiles to advance for in vivo evaluation.

Imidazo-fused oxazolo[4,5-b]pyridine and imidazo-fused thiazolo[4,5-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same

-

Page/Page column 25, (2010/11/30)

The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.

IMIDAZO-FUSED OXAZOLO[4,5-B]PYRIDINE AND IMIDAZO-FUSED THIAZOLO[4,5-B]PYRIDINE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

-

Page 153, (2010/02/09)

The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I),[chemical structure] wherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 805319-85-1