80540-92-7

Basic information

• Product Name: α-acetyl-p-dimethylaminocinnamonitrile
• CAS NO: 80540-92-7
• Molecular Weight: 214.267
• Mol File: 80540-92-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-acetyl-p-dimethylaminocinnamonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α-acetyl-p-dimethylaminocinnamonitrile(80540-92-7)
• EPA Substance Registry System: α-acetyl-p-dimethylaminocinnamonitrile(80540-92-7)

Safety Data

• Hazardous Substances Data: 80540-92-7(Hazardous Substances Data)

Upstream product

• 3405-77-4 5-methylisoxazole 3-carboxylic acid 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 32954-25-9 N-<(dimethylamino)-carbonyl>-5-methyl-3-isoxazolecarboxamide 
• 7186-53-0 3-(2-oxazolin-2-yl)-5-methylisoxazole 

Relevant articles and documents

Analytical Studies on Isoxazoles. I. A New Colorimetric Determination of 5-Substituted 3-Isoxazolecarboxylic Acids and Their Derivatives

A new colorimetric method for the determination of 5-methyl-3-isoxazolecarboxylic acid (MIA) and 5-phenyl-3-isoxazolecarboxylic acid (PIA) was established.This method is based on the decomposition of 5-substituted 3-isoxazolecarboxylic acids to their corresponding β-ketonitriles, followed by condensation with p-dimethylaminobenzaldehyde (DABA).The 5-carboxylic isomers caused no interference in the determination of MIA and PIA.Further applications of this method to peroxisal (II), N--5-methyl-3-isoxazolecarboxamide (III), and 3-(2-oxazolin-2-yl)-5-methylisoxazole (IV), by decomposition to the corresponding 5-substituted 3-isoxazolecarboxylic acids, followed by the color reaction with DABA, are described.Keywords-colorimetric determination; 3-isoxazolecarboxylic acids; p-dimethylaminobenzaldehyde; Knoevenagel condensation reaction; α-benzoyl-p-dimethylaminocinnamonitrile; α-acetyl-p-dimethylaminocinnamonitrile.