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1-(3-C-methyl-β-D-ribofuranosyl)uracil, also known as 3-methyluridine, is a nucleoside composed of uracil and a 3-methyl-β-D-ribofuranose sugar moiety. This chemical is a derivative of uridine, a naturally occurring nucleoside found in RNA, with a methyl group attached to the third carbon of the ribose sugar. 3-methyluridine plays a role in various biological processes, including the synthesis of certain tRNAs and the regulation of gene expression. It is also used as a research tool in molecular biology to study the structure and function of nucleic acids. The presence of the methyl group in 3-methyluridine can affect its interactions with enzymes and other biomolecules, making it an important compound for understanding the chemistry and biology of nucleic acids.

80541-15-7

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80541-15-7 Usage

Type

Modified nucleoside

Found in

RNA

Derived from

Uracil (a common nucleobase in RNA)

Structural feature

Contains a ribofuranosyl sugar moiety

Attachment position

1-position of the uracil base

Modification

C-methyl group at the 3-position of the ribofuranosyl sugar

Purpose of modification

Enhances stability of the nucleoside and potentially alters binding properties

Applications

Studied for therapeutic applications

Potential uses

Antiviral and anticancer drugs

Check Digit Verification of cas no

The CAS Registry Mumber 80541-15-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,4 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 80541-15:
(7*8)+(6*0)+(5*5)+(4*4)+(3*1)+(2*1)+(1*5)=107
107 % 10 = 7
So 80541-15-7 is a valid CAS Registry Number.

80541-15-7Relevant academic research and scientific papers

SYNTHESIS AND PROPERTIES OF 3'-C-METHYLNUCLEOSIDES AND THEIR PHOSPHORIC ESTERS

Mikhailov, Sergey N.,Beigelman, Leon N.,Gurskaya, Galyna V.,Padyukova, Nelly Sh.,Yakovlev, Gennady I.,Karpeisky, Marat Ya.

, p. 75 - 96 (1983)

3'-C-Methyluridine and 3'-C-methylcytidine were synthesized in 11 steps starting from D-glucose.The conformation of 3'-C-methylnucleosides was studied in solution and in the cystal by using the techniques of c.d., 1H-n.m.r spectroscopy, and X-ray diffract

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