80585-44-0

Upstream product

• 67941-87-1 cyclohexylammonium S,S-diphenyl phosphorodithioate 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 80585-43-9 Dithiophosphoric acid O-[(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester 

Downstream Products

• 104655-91-6 C₇₄H₇₂N₄O₁₇P₂S₂ 
• 116980-77-9 C₅₄H₅₃N₄O₁₄PS 
• 104655-92-7 Thiophosphorochloridic acid O-[(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester S-phenyl ester 

Relevant academic research and scientific papers

Biologically active oligodeoxyribonucleotides, 5. 5'-end-substituted d(TGGGAG) possesses anti-human immunodeficiency virus type 1 activity by forming a G-quadruplex structure

A series of hexadeoxyribonucleotides (6-mers), d(TGGGAG), substituted with a variety of aromatic groups at the 5'-end were synthesized and tested for anti-human immunodeficiency virus type 1 (HIV-1) activity. While unmodified d(TGGGAG) (31) had no anti-HI

SELF-COMPLEMENTARY TETRADEOXYRIBONUCLEOSIDE TRIPHOSPHATES. CONVENIENT CHEMICAL PREPARATION AND SPECTROSCOPIC STUDIES IN SOLUTION

Eight kinds of self-complementary tetradeoxyribonucleoside triphosphates were prepared by a simplified method which enabled us to omit purification of synthetic intermediates and provided the tetramers very rapidly and conveniently.The tetramers were characterized by enzyme assay and their conformations were studied by the use of UV and CD spectroscopic methods under various conditions.The detailed analysis of the CD spectra suggested that conformation of the tetramer duplexes was dependent on the sequence.