80598-90-9Relevant academic research and scientific papers
GENERATION OF sec-THIOAMIDE DIANIONS AND THEIR REGIOSELECTIVE REACTION WITH ELECTROPHILES.
Tamaru, Y.,Kagotani, M.,Furukawa, Y.,Amino, Y.,Yoshida, Z.
, p. 3413 - 3416 (2007/10/02)
The enolates of sec-thioamides 8, which are generated by three different methods (scheme II and equation 1), are alkylated selectively at the α-carbon to the thiocarbonyl group.The unusual β'-lithiation to provide an intermediate 11 is observed for N-methyl-α,β-dimethylthioacrylamide and N-methylthiocyclohexenecarboxamide.
