80615-39-0Relevant academic research and scientific papers
Enantioselective and Regioselective Hydroetherification of Alkynes by Gold-Catalyzed Desymmetrization of Prochiral Phenols with P-Stereogenic Centers
Zheng, Yin,Guo, Linna,Zi, Weiwei
supporting information, p. 7039 - 7043 (2018/11/24)
The gold(I)-catalyzed enantioselective hydroetherification of alkynes was achieved via desymmetrization of prochiral bisphenols bearing P-stereogenic centers. (S)-DTBM-Segphos(AuCl)2/AgNTf2 proved to be a highly efficient catalyst system for this transformation, affording P-chiral cyclic phosphine oxides in good yields with high enantioselectivities (with up to 99% ee). The same catalyst system allowed for the enantioselective desymmetrization of dialkynes. Synthetic transformations of the cyclization products afforded other P-chiral molecules with high enantiospecificity.
SYNTHESIS AND SUBSTITUENT EFFECT ON 31P NMR CHEMICAL SHIFT OF ORTHO-HYDROXYARYL DIALKYL PHOSPHINE OXIDES
Li, Shusen,Wang, Guoquan
, p. 119 - 129 (2007/10/02)
In this paper, the synthetic methods for the preparation of o-hydroxyaryl dialkyl phosphine oxides (1) are introduced.The title compounds with low bulky substituent are synthesized successfully by the reactions of Grignard reagents with diethyl o-hydroxya
AN EFFICIENT SYNTHESIS OF 2-HYDROXYPHENYLPHOSPHONATES
Melvin, L. S.
, p. 3375 - 3376 (2007/10/02)
The high yield conversion of phenols into diethyl 2-hydroxyphenylphosphonates via base catalyzed rearrangement of diethyl phenyl phosphates has been achieved.
