80615-75-4Relevant academic research and scientific papers
ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXYISOBUTYRIC ACID: A USEFUL SYNTHON IN THE SYNTHESIS OF POLYPROPIONATE-TYPE NATURAL PRODUCTS
Choy, William,Ma, Philip,Masamune, Satoru
, p. 3555 - 3556 (2007/10/02)
The aldol reaction of formaldehyde with the dicyclopentylborinyl enolate derived from S-(or R-) 1-tert-butyldimethylsilyloxy-1-cyclohexylbutan-2-one, followed by desilylation and sodium meta-periodate oxidation, provides R-(or S-) β-hydroxyisobutyric acid.
